Considering that most health issues from a skinned knee, twisted ankle or even normal wear and tear involve some level of pain, it only makes sense to decipher the mechanism behind this feeling and find a means to manage it. For centuries, various remedies provided some pain relief until a breakthrough occurred in the discovery that the hormone-like compounds called prostaglandins, which are the cause of inflammation and thus the producers of pain, could be blocked. By inhibiting an enzyme known as Cyclooxygenase-2 (COX-2), which triggers the release of prostaglandins, there exists a solution to pain management.
Package Type: 60 Caps
Retail: $ 11.95
Our price: $9.56
Warnings:
Precautions: See bottle for specific useage.
Notes: What’s in C-2 Relief
While COX-2 inhibition may seem to clearly describe one pharmacological effect of several common and widely recognized natural products, such a benefit seems in favor of the following compounds serving as natural modulators of pain:

Syzygium Aromaticum, more commonly known as Cloves, have natural anesthetic properties.

White Willow Bark contains salicylic acid, which is the active ingredient in aspirin. Aspirin was originally derived from white willow bark but is now made synthetically.

Curcuminoids are powerful anti-inflammatory agents.

Morinda Officinalis contains a wide variety of beneficial phytochemicals, some of which are not found in any other known plant. Phytochemicals are natural chemicals found in plants that work synergistically to enhance biologically the expression of each individual component found in Noni including its uses for pain and inflammation.

Boswella Serrata has been used for thousands of years and has produced tremendous results in treating pain and inflammation by blocking the synthesis of leukotrienes, which can trigger inflammation.
Ingredients:

HOW HEADMED CAN HELP
HeadMed contains Petasides Hybridus (butterbur) which is a perennial shrub found throughout Europe as well as parts of Asia and North America and that has been used medicinally for centuries. Currently, the primary therapeutic uses for Petasites Hybridus are for prophylactic treatment of migraines, and as an antispasmodic agent for chronic cough or asthma. It has also been used successfully in preventing gastric ulcers, and in treating patients with irritable bladder and urinary tract spasms.
Package Type: 60 Caps
Retail: $ 16.95
Our price: $13.56
Warnings:
Precautions: Please see bottle for specific instructions.
Notes: ACTIVE CONSTITUENTS AND MECHANISM OF ACTION
Extracts of Petasites Hybridus are prepared from the rhizomes, roots, and leaves. The main active constituents are petasin and isopetasin. Petasin is responsible for the anti-spasmodic properties of the plant by reducing spasms in smooth muscle and vascular walls, in addition to providing an anti-inflammatory effect by inhibiting leukotriene synthesis. Prostaglandins are important mediators in the inflammatory process and isopetasin's positive impact on prostaglandin metabolism contributes to the effectiveness of Petasites extracts.

The active constituents of Petasites Hybridus have an antispasmodic effect on vascular walls and appear to have an affinity for cerebral blood vessels. As a result, the ability of HeadMed to reduce smooth muscle spasm suggests it may be a useful therapeutic tool in terms of its anti-inflammatory properties.

CLINICAL INDICATIONS
Two clinical studies using 50 mg of a standardized Petasites Hybridus extract twice daily for 12 weeks demonstrated its effectiveness as a prophylactic treatment for migraines. Both studies were double-blind, placebo controlled, and involved a total of 128 patients. The results of the two studies showed a significant reduction (as much as 60%) in frequency of migraine attacks compared to placebo. Other improvements in the test group included a reduction in the number of days with migraines per month, a decrease in migraine-associated symptoms, and diminished duration and intensity of pain. No adverse reactions were reported in either study. Petasites Hybridus’ high degree of efficacy and excellent tolerability accentuates its value in the prophylactic treatment of migraines.
Ingredients:

Cortisol Appetite Control works in two ways. First, it stops us from overeating. And second, it speeds up our metabolism so we burn more calories from the food we do eat. The result? Normal appetite, high metabolism and a lean body.
Package Type: 75 Gel Caps
Retail: $ 19.95
Our price: $15.96
Warnings:
Precautions: Take 1 gel cap in the morning. For more rapid results, take 2 gel caps in the morning. For optimal results, use in conjunction with a low calorie diet and exercise program.
Notes: The bioavailability, absorption and potency of this formula is 'super charged' with Bioperine.
Ingredients: No artificial color or preservatives.